Patients
Satellos is developing SAT-3247, a first-in-class oral treatment designed to restore muscle regeneration for people living with Duchenne muscular dystrophy. With encouraging early safety results, we are advancing our clinical program with urgency, care, and a steadfast commitment to safety.
At Satellos, our mission is to develop new medicines that restore muscle regeneration for people living with muscle diseases. Our potential treatment, SAT-3247, is focused on Duchenne muscular dystrophy — a condition where the body’s natural ability to repair muscle is severely impaired. We’re advancing our science with urgency and care, always focused on delivering meaningful results for the individuals and families affected by Duchenne.
We have completed our first-in-human Phase 1a/b clinical trial evaluating SAT-3247 in Healthy Volunteers and Adults with Duchenne, and have initiated a long-term follow-up study for patients that participated in that trial.
SAT-3247 is an oral treatment we’re developing to help improve how muscle repairs itself in people with Duchenne. The loss of dystrophin disrupts a key signal that guides muscle stem cells to respond to damage. SAT-3247 is designed to restore that signal by targeting a protein called AAK1. By doing so, it helps muscle stem cells divide and function more effectively — supporting the body’s natural ability to repair and rebuild muscle. This approach has the potential to benefit many people living with Duchenne, no matter their specific genetic mutation or severity of disease.
SAT-3247-LT-001 – Long-Term Follow-Up Study
Primary Objectives
- Monitor long-term safety and tolerability
- Track exploratory biomarkers of muscle regeneration
- Track potential effects on function
Participants
Individuals who completed the initial Phase 1b trial
Location
Melbourne, Australia
For more information on this study, visit
clinicaltrials.gov/study/NCT06867107

Charlie’s Story
A family’s long-awaited joy turned to heartbreak when their young son was diagnosed with Duchenne muscular dystrophy. Through determination, hope, and the promise of science, they’ve found a path forward — but questions remain about what the future will hold. Read their story of love, resilience, and daring to dream of a different outcome.
We recognize the urgent need for new treatment options for families living with Duchenne. While we are working quickly to develop SAT-3247, it is currently only available through clinical trials.

Where We Are Now
- Safety results in adults with Duchenne are encouraging after 28 days of treatment.
- We require more safety data for children and longer-term use before broader access can be safely considered.
What This Means
- Safety is our top priority, and current regulations require comprehensive data for both safety and efficacy.
- We understand this is frustrating, and we are committed to advancing as quickly as possible, while prioritizing safety.
- We will keep you informed and continue exploring ways to make this treatment available to more people living with Duchenne.
Satellos is committed to reaching people of all ages with SAT-3247 as quickly as possible, guided by the data and with safety always in mind.
Satellos regularly reviews its policies to ensure they align with applicable laws and regulations. We may update this policy at any time as needed.